Marvel rise of the imperfects, it has so much potential especially on the new gens, they could expand it so far, and have a huge roster, including versus modes (such as tag team, but of cause it would be different imagine, the line up you could have), multiplayer, story mode.
www.youtube.com/watch?v=VxEqfspOsDs
The open combat was done so well, and it could be done so much better, if on the xbox 360, Ps3, Pc's, etc, this is the step they should be taking instead of one on one versus games.